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Immunology for University Students
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Resources and Material for Lecturers and Students - Immunology (University level)
Curated by
Alfredo Corell
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Differences in the cell morphology of macrophages in either pro-inflammatory (M1)-polarizing or pro-healing (M2)-polarizing conditions have been previously observed. As described in this study, M1-polarizing stimuli (LPS plus IFNγ) cause cells to flatten into a round, pancake-like shape, whereas M2-polarizing stimuli (IL-4 and IL-13) induce an elongated cell shape.