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With depression affecting around 1 in 10 of us at some point during our lives, the need for new and improved treatments is a top priority for researchers – and it appears that spinal cord stimulation could be one route for experts to investigate. A team led by researchers at the University of Cincinnati College of Medicine devised a pilot clinical trial in which a little black box was placed on the spinal cord of 20 volunteers with depression, with one electrode on the back and one on the right shoulder.

Two new drugs for treating obesity are on course to become available in the next few years — and they offer advantages beyond those of the highly effective blockbuster drugs already on the market. The first, called orforglipron, is easier to use and to produce, and it will probably be cheaper than existing treatments. The second, retatrutide, has an unprecedented level of efficacy, and could raise the bar for pharmacological obesity treatment.

Painful periods are common. More than half of people who menstruate have some pain for up to three days a month, typically throbbing or cramping in the lower abdomen. Digestive changes – such as vomiting, gas, bloating, diarrhoea and a “bubbling gut” – are also common around the time of menstruation. There are many treatments for period pain (known medically as dysmenorrhoea). Not all these treatments are well-tolerated or work for everyone. We’re learning more about food’s role in influencing inflammation in our body. So, could eating or avoiding certain foods help with painful periods? Here’s what we know based on high-quality research.

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